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Article

Relapse of Acute Lymphoblastic Leukemia in Children in the Context of Microarray Analyses

18 Jan 2011

Abstract excerpt

Over the last four decades the treatment of patients with newly diagnosed childhood acute lymphoblastic leukemia (ALL) has improved remarkably. However, still about 20% of children with ALL relapse despite risk-adapted polychemotherapy. The prognosis of relapsed ALL is relatively poor, even with modern aggressive chemotherapy. Identification of the biological and genetic mechanisms contributing to recurrence in...

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PMID: 21246408
DOI: 10.1007/s00005-010-0110-1

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