Article
Genome-wide expression analysis of paired diagnosis-relapse samples in ALL indicates involvement of pathways related to DNA replication, cell cycle and DNA repair, independent of immune phenotype.
Leukemia - 1 Mar 2010
Staal F J T, de Ridder D, Szczepanski T, Schonewille T, van der Linden E C E, van Wering E R, van der Velden V H J, van Dongen J J M
Abstract excerpt
Almost a quarter of pediatric patients with acute lymphoblastic leukemia (ALL) suffer from relapses. The biological mechanisms underlying therapy response and development of relapses have remained unclear. In an attempt to better understand this phenomenon, we have analyzed 41 matched diagnosis-r...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.