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Article

A polymorphism in PTPN2 gene is associated with an earlier onset of type 1 diabetes.

Immunogenetics - 1 Apr 2011

Espino-Paisan Laura, de la Calle Hermenegildo, Fernández-Arquero Miguel, Figueredo Maria Angeles, de la Concha Emilio G, Urcelay Elena, Santiago Jose Luis

Abstract excerpt

The Wellcome Trust Case Control Consortium (WTCCC) genome-wide study found association of PTPN2 with three autoimmune diseases, among them is type 1 diabetes (T1D). This result was confirmed by a follow-up study that pointed to new independent signals within the region. However, both studies were performed in patients with an early-onset T1D. We aimed at replicating the previous results and studying the influence...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Protein Tyrosine Phosphatase, Non-Receptor Type 2

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Source

Identifiers

PMID: 21246196
DOI: 10.1007/s00251-010-0500-x

Genes

PTPN2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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A polymorphism in PTPN2 gene is associated with an earlier onset of type 1 diabetes.PMID 21246196Read ↗

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