Article
Lysyl oxidase-like 3b is critical for cartilage maturation during zebrafish craniofacial development.
Matrix biology : journal of the International Society for Matrix Biology - 1 Apr 2011
van Boxtel Antonius L, Gansner John M, Hakvoort Henk W J, Snell Heather, Legler Juliette, Gitlin Jonathan D
Abstract excerpt
Vertebrate craniofacial development requires coordinated morphogenetic interactions between the extracellular matrix (ECM) and the differentiating chondrocytes essential for cartilage formation. Recent studies reveal a critical role for specific lysyl oxidases in ECM integrity required for embryonic development. We now demonstrate that loxl3b is abundantly expressed within the head mesenchyme of the zebrafish and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
