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Article

Defective neural crest migration revealed by a Zebrafish model of Alx1-related frontonasal dysplasia

11 Oct 2012

Abstract excerpt

Frontonasal dysplasia (FND) refers to a class of midline facial malformations caused by abnormal development of the facial primordia. The term encompasses a spectrum of severities but characteristic features include combinations of ocular hypertelorism, malformations of the nose and forehead and clefting of the facial midline. Several recent studies have drawn attention to the importance of Alx homeobox...

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PMID: 23059813
DOI: 10.1093/hmg/dds423

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