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Article

Immunocompetent cell functions in Ph+ acute lymphoblastic leukemia patients on prolonged Imatinib maintenance treatment.

Cancer immunology, immunotherapy : CII - 1 Apr 2011

Maggio Roberta, Peragine Nadia, De Propris Maria Stefania, Vitale Antonella, Elia Loredana, Calabrese Elisabetta, Della Starza Irene, Intoppa Stefania, Milani Maria Laura, Guarini Anna, Foà Robin

Abstract excerpt

Imatinib mesylate (Imatinib) is a potent inhibitor of defined tyrosine kinases and is effectively used for the treatment of malignancies characterized by the constitutive activation of these tyrosine kinases, such as Philadelphia chromosome-positive (Ph(+)) leukemias and gastrointestinal stromal tumors. Suppressive as well as stimulating effects of this drug on T lymphocytes or dendritic cells (DC), which play a...

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Identifiers

PMID: 21240485
DOI: 10.1007/s00262-010-0966-2
PMCID: PMC11029509

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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