Cytokine modulation of the susceptibility of acute T-lymphoblastic leukemia cell lines to LAK activity.

Article

Cytokine modulation of the susceptibility of acute T-lymphoblastic leukemia cell lines to LAK activity.

Leukemia - 1 Mar 1993

Cesano A, Clark S C, Santoli D

Abstract excerpt

We studied the regulatory effects of various cytokines on the susceptibility to lymphocyte-mediated lysis of cell lines established from patients with acute T-lymphoblastic leukemia (T-ALL). None of the cytokines tested affected the sensitivity of these targets to natural killer activity. In cont...

Topics

Cell Division
Child
Cytokines
Drug Screening Assays, Antitumor
Gene Rearrangement, T-Lymphocyte
Humans
Killer Cells, Lymphokine-Activated
Leukemia-Lymphoma, Adult T-Cell
Phenotype
Receptors, Antigen, T-Cell
Tumor Cells, Cultured

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