ADRB2 and LEPR gene polymorphisms: synergistic effects on the risk of obesity in Japanese.

doi:10.1038/oby.2010.322

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Article

ADRB2 and LEPR gene polymorphisms: synergistic effects on the risk of obesity in Japanese.

Obesity (Silver Spring, Md.) - 1 Jul 2011

Pereira Tiago V, Mingroni-Netto Regina C, Yamada Yoshiji

Abstract excerpt

The objective of the present study was to validate a recently reported synergistic effect between variants located in the leptin receptor (LEPR) gene and in the β-2 adrenergic receptor (ADRB2) gene on the risk of overweight/obesity. We studied a middle-aged/elderly sample of 4,193 nondiabetic Japanese subjects stratified according gender (1,911 women and 2,282 men). The LEPR Gln223Arg (rs1137101) variant as well...

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Source

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Identifiers

PMID: 21233812
DOI: 10.1038/oby.2010.322

Genes

ADRB2
LEPR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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