Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Interactions between variants in the beta3-adrenergic receptor and peroxisome proliferator-activated receptor-gamma2 genes and obesity.

Diabetes care - 1 Apr 2001

Hsueh W C, Cole S A, Shuldiner A R, Beamer B A, Blangero J, Hixson J E, MacCluer J W, Mitchell B D

Abstract excerpt

OBJECTIVE: Previous studies have reported modest associations between measures of obesity and the Trp64-Arg variant of the beta3-adrenergic receptor (ADRbeta3) and the Pro12Ala variant of the peronisome proliferator-activated receptor (PPAR)-gamma2. We hypothesized that these single gene variants may mark mutations that act through convergent pathways to produce synergistic effects on obesity. RESEARCH DESIGN AND...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adipose Tissue
Share to Arteriosclerosis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Leptin

Share to Lymphocytes

Share to Mexican Americans

Share to Receptors, Adrenergic, beta-3

Share to Receptors, Cytoplasmic and Nuclear

Source

Identifiers

PMID: 11315829
DOI: 10.2337/diacare.24.4.672

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Interactions between variants in the beta3-adrenergic receptor and peroxisome proliferator-activated receptor-gamma2 genes and obesity.PMID 11315829Read ↗

Gene-gene interaction between PPAR gamma 2 and ADR beta 3 increases obesity risk in children and adolescents.Semantic proximity Read ↗

Identification of an interactive effect of beta3- and alpha2b-adrenoceptor gene polymorphisms on fat mass in Caucasian women.Semantic proximity Read ↗

TRP64ARG beta 3-adrenergic receptor and obesity in Mexican Americans.Semantic proximity Read ↗

Multilocus analyses of seven candidate genes suggest interacting pathways for obesity-related traits in Brazilian populations.Semantic proximity Read ↗

Genetic variation in fatty acid-binding protein-4 and peroxisome proliferator-activated receptor gamma interactively influence insulin sensitivity and body composition in males.Semantic proximity Read ↗

Single nucleotide variants in the beta2-adrenergic and beta3-adrenergic receptor genes explained 18.3% of adolescent obesity variation.Semantic proximity Read ↗

Relationship between obesity, adipocytokines, and blood pressure: possible common genetic and environmental factors.Semantic proximity Read ↗

A paired sibling analysis of the beta-3 adrenergic receptor and obesity in Mexican Americans.Semantic proximity Read ↗

Common variation at PPARGC1A/B and change in body composition and metabolic traits following preventive interventions: the Diabetes Prevention Program.Semantic proximity Read ↗

Patterns of association between PPARgamma genetic variation and indices of adiposity and insulin action in African-Americans and whites: the CARDIA Study.Semantic proximity Read ↗

The Trp64Arg polymorphism in β3 adrenergic receptor (ADRB3) gene is associated with adipokines and plasma lipids: a systematic review, meta-analysis, and meta-regression.Semantic proximity Read ↗

Gene-gene interactions among genetic variants from obesity candidate genes for nonobese and obese populations in type 2 diabetes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.