Article
Evaluation of 41 candidate gene variants for obesity in the EPIC-Potsdam cohort by multi-locus stepwise regression.
PloS one - 1 Jan 2013
Knüppel Sven, Rohde Klaus, Meidtner Karina, Drogan Dagmar, Holzhütter Hermann-Georg, Boeing Heiner, Fisher Eva
Abstract excerpt
OBJECTIVE: Obesity has become a leading preventable cause of morbidity and mortality in many parts of the world. It is thought to originate from multiple genetic and environmental determinants. The aim of the current study was to introduce haplotype-based multi-locus stepwise regression (MSR) as a method to investigate combinations of unlinked single nucleotide polymorphisms (SNPs) for obesity phenotypes....
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