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Article

Copy number variations at the Prader-Willi syndrome region on chromosome 15 and associations with obesity in whites.

Obesity (Silver Spring, Md.) - 1 Jun 2011

Chen Yuan, Liu Yong-Jun, Pei Yu-Fang, Yang Tie-Lin, Deng Fei-Yan, Liu Xiao-Gang, Li Ding-You, Deng Hong-Wen

Abstract excerpt

Obesity is a serious health problem with strong genetic determination. Copy number variation (CNV) is a common type of genomic variant associated with some complex human diseases. However, it is not clear how CNVs contribute to the etiology of obesity. In this study, we examined 1,000 unrelated US whites to search for CNVs that may predispose to obesity. We focused our analyses on the Prader-Willi syndrome (PWS)...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 21233802
DOI: 10.1038/oby.2010.323
PMCID: PMC4512297

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