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Article

DNA sequencing and copy number variation analysis of MCHR2 in a cohort of Prader Willi like (PWL) patients.

Obesity research & clinical practice - 1 Jan 2000

Geets Ellen, Aerts Evi, Verrijken An, Van Hoorenbeeck Kim, Verhulst Stijn, Van Gaal Luc, Van Hul Wim

Abstract excerpt

BACKGROUND: Prader Willi Syndrome (PWS) is a syndromic form of obesity caused by a chromosomal aberration on chromosome 15q11.2-q13. Patients with a comparable phenotype to PWS not carrying the 15q11.2-q13 defect are classified as Prader Willi like (PWL). In literature, PWL patients do frequently harbor deletions at 6q16, which led to the identification of the single-minded 1 (SIM1) gene as a possible cause for...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 29066024
DOI: 10.1016/j.orcp.2017.10.001

Genes

MCHR2
SIM1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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