Article
Activity and polymorphisms of butyrylcholinesterase in a Polish population.
Chemico-biological interactions - 25 Nov 2016
Jasiecki Jacek, Jońca Joanna, Żuk Monika, Szczoczarz Anna, Janaszak-Jasiecka Anna, Lewandowski Krzysztof, Waleron Krzysztof, Wasąg Bartosz
Abstract excerpt
Butyrylcholinesterase (BChE) activity assay and inhibitor phenotyping can help to identify individuals at risk of prolonged paralysis following the administration of neuromuscular blocking agents, like succinylcholine, pesticides and nerve agents. In this study, the activity of BChE and its sensitivity to inhibition by dibucaine and fluoride was evaluated in 1200 Polish healthy individuals. In addition, molecular...
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