Article
Alterations to N-linked oligosaccharides which affect intracellular transport rates and regulated secretion but not sorting of lysosomal acid phosphatase in Dictyostelium discoideum.
Archives of biochemistry and biophysics - 15 Nov 1990
Bush J M, Ebert D L, Cardelli J A
Abstract excerpt
The importance of N-linked oligosaccharides and their associated modifications in the transport, sorting, and secretion of lysosomal acid phosphatase was investigated using three mutant Dictyostelium cell lines. These mutants synthesize altered N-linked oligosaccharides with the following propert...
Topics
- Acetylglucosaminidase
- Acid Phosphatase
- Dictyostelium
- Fluorescent Antibody Technique
- Glycosylation
- Kinetics
- Lysosomes
- Mannosyl-Glycoprotein Endo-beta-N-Acetylglucosaminidase
- Mutation
- Oligosaccharides
- Protein Processing, Post-Translational
- Subcellular Fractions