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Article

Biochemical and genetic analysis of the biosynthesis, sorting, and secretion of Dictyostelium lysosomal enzymes.

Developmental genetics - 1 Jan 1990

Cardelli J A, Schatzle J, Bush J M, Richardson J, Ebert D, Freeze H

Abstract excerpt

Dictyostelium discoideum is a useful system to study the biosynthesis of lysosomal enzymes because of the relative ease with which it can be manipulated genetically and biochemically. Previous studies have revealed that lysosomal enzymes are synthesized in vegetatively growing amoebae as glycosyl...

Topics

Acid Phosphatase
Biological Transport
Blotting, Northern
Dictyostelium
Electrophoresis, Polyacrylamide Gel
Hydrogen-Ion Concentration
Hydrolysis
Lysosomes
Mannosidases
Mutation
Oligosaccharides
RNA, Messenger

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

alpha-Mannosidase

beta-Galactosidase

Source

Identifiers

PMID: 2128926
DOI: 10.1002/dvg.1020110522

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2128926-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Biochemical and genetic analysis of the biosynthesis, sorting, and secretion of Dictyostelium lysosomal enzymes.PMID 2128926Read ↗

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