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Article

Evidence that XRN4, an Arabidopsis homolog of exoribonuclease XRN1, preferentially impacts transcripts with certain sequences or in particular functional categories.

RNA (New York, N.Y.) - 1 Mar 2011

Rymarquis Linda A, Souret Frederic F, Green Pamela J

Abstract excerpt

One of the major players controlling RNA decay is the cytoplasmic 5'-to-3' exoribonuclease, which is conserved among eukaryotic organisms. In Arabidopsis, the 5'-to-3' exoribonuclease XRN4 is involved in disease resistance, the response to ethylene, RNAi, and miRNA-mediated RNA decay. Curiously, XRN4 appears to display selectivity among its substrates because certain 3' cleavage products formed by miRNA-mediated...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 21224377
DOI: 10.1261/rna.2467911
PMCID: PMC3039149

Genes

AGO1
XRN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Evidence that XRN4, an Arabidopsis homolog of exoribonuclease XRN1, preferentially impacts transcripts with certain sequences or in particular functional categories.PMID 21224377Read ↗

The exoribonuclease XRN4 is a component of the ethylene response pathway in Arabidopsis.Semantic proximity Read ↗

AtXRN4 degrades mRNA in Arabidopsis and its substrates include selected miRNA targets.Semantic proximity Read ↗

The 5’-3’ exoribonuclease XRN4 modulates the plant circadian network in ArabidopsisSemantic proximity Read ↗

Arabidopsis FIERY1, XRN2, and XRN3 are endogenous RNA silencing suppressors.Semantic proximity Read ↗

Monitoring of XRN4 Targets Reveals the Importance of Cotranslational Decay during Arabidopsis Development.Semantic proximity Read ↗

Loss of Arabidopsis 5'-3' Exoribonuclease AtXRN4 Function Enhances Heat Stress Tolerance of Plants Subjected to Severe Heat Stress.Semantic proximity Read ↗

Defective XRN3-mediated transcription termination in Arabidopsis affects the expression of protein-coding genes.Semantic proximity Read ↗

XRN 5'→3' exoribonucleases: structure, mechanisms and functions.Semantic proximity Read ↗

ETHYLENE-INSENSITIVE5 encodes a 5'-->3' exoribonuclease required for regulation of the EIN3-targeting F-box proteins EBF1/2.Semantic proximity Read ↗

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XRN4 and LARP1 are required for a heat-triggered mRNA decay pathway involved in plant acclimation and survival during thermal stress.Semantic proximity Read ↗

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