Coagulation factor and protease pathways in thrombosis and cardiovascular disease.

doi:10.1160/TH17-02-0079

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Article

Coagulation factor and protease pathways in thrombosis and cardiovascular disease.

Thrombosis and haemostasis - 28 Jun 2017

Ten Cate Hugo, Hackeng Tilman M, García de Frutos Pablo

Abstract excerpt

The biochemical characterisation of the proteolytic pathways that constitute blood coagulation was one of the most relevant achievements in biomedical research during the second half of the 20th century. Understanding these pathways was of crucial importance for improving global health through application in haemostasis and thrombosis pathologies. Immediately after the cloning of the genes corresponding to these...

Topics

Blood Coagulation
Blood Coagulation Factors
Cardiovascular Diseases
Hemostasis
Humans
Mutation
Peptide Hydrolases
Proteolysis
Reperfusion Injury
Thrombosis

Source

Open in PubMed

Identifiers

PMID: 28594052
DOI: 10.1160/TH17-02-0079

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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