Article
Hypercoagulability in various autoimmune diseases: no association with factor V Leiden mutation.
Haematologia - 1 Jan 2000
Regéczy N, Balogh I, Lakos G, Zeher M, Bodolay E, Szücs G, Kiss E, Ajzner E, Szegedi G
Abstract excerpt
The coagulation factor V Leiden mutation, leading to resistance to activated protein C (APC), is the most common inherited risk factor for venous thrombosis. In various systemic autoimmune diseases the hypercoagulable state was shown to be associated with the presence of antiphospholipid antibodies (aPL). Our aim was to determine the prevalence of both, Leiden mutation and aPL in autoimmune diseases and their...
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