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Article

Cadmium induces phosphorylation and stabilization of c-Fos in HK-2 renal proximal tubular cells.

Toxicology and applied pharmacology - 15 Mar 2011

Iwatsuki Mamiko, Inageda Kiyoshi, Matsuoka Masato

Abstract excerpt

We examined the effects of cadmium chloride (CdCl₂) exposure on the expression and phosphorylation status of members of the Fos family, components of the activator protein-1 transcription factor, in HK-2 human renal proximal tubular cells. Following the exposure to CdCl₂, the expression of c-fos, fosB, fra-1, and fra-2 increased markedly, with different magnitudes and time courses. The levels of Fos family...

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Identifiers

PMID: 21219922
DOI: 10.1016/j.taap.2010.12.015

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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