Article
[V89L polymorphism of the testosterone 5-alpha-reductase II gene and prognostic factors of prostate cancer].
Zhonghua nan ke xue = National journal of andrology - 1 Nov 2010
Tong Ming, Jin Yan-Yang, Li Gang, Liu Si-Ming, Ji Chun-Dong
Abstract excerpt
OBJECTIVE: To investigate the association of V89L polymorphism of the SRD5A2 gene with the prognostic factors of prostate cancer (PCa). METHODS: We identified the V89L polymorphic sites of the SRD5A2 gene after Rsa-1 restriction enzyme digestion, observed the distribution of V89L (VV, VL and LL) polymorphism in 112 PCa and 89 benign prostate hyperplasia (BPH) patients, and determined the association of V89L...
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