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Article

Longer (TA)n repeat but not A49T and V89L polymorphisms in SRD5A2 gene may confer prostate cancer risk in South Indian men.

Journal of andrology - 1 Jan 2000

Rajender Singh, Vijayalakshmi Krishnaswamy, Pooja Singh, Madhavi Sakhamuri, Paul Solomon F D, Vettriselvi V, Shroff Sunil, Singh Lalji, Thangaraj Kumarasamy

Abstract excerpt

Testosterone is converted to 5 alpha-dihydrotestosterone (DHT) by 5 alpha-reductase enzyme, which is encoded by the SRD5A2 gene. DHT is the main androgen responsible for prostate growth. We have analyzed the complete coding region of the SRD5A2 gene in 87 histologically confirmed prostate cancer (PC) patients, 40 benign prostatic hyperplasia (BPH) cases, and 96 control samples from southern parts of India. The...

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Identifiers

PMID: 19443907
DOI: 10.2164/jandrol.108.007377

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Longer (TA)n repeat but not A49T and V89L polymorphisms in SRD5A2 gene may confer prostate cancer risk in South Indian men.PMID 19443907Read ↗

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