Article
Mouse lung and spleen natural killer cells have phenotypic and functional differences, in part influenced by macrophages.
PloS one - 1 Jan 2012
Michel Tatiana, Poli Aurélie, Domingues Olivia, Mauffray Marion, Thérésine Maud, Brons Nicolaas H C, Hentges François, Zimmer Jacques
Abstract excerpt
NK cells are lymphocytes of the innate immune system which are a first line of defense against infections and tumor cells, in bone marrow and peripheral organs like lung and spleen. The lung is an organ in contact with respiratory pathogens and the site of inflammatory disorders triggered by the respiratory environment. In contrast, spleen is a lymphatic organ connected to the blood system which regulates the...
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