Article
NK-cell phenotype at interruption underlies widely divergent duration of CD4+-guided antiretroviral treatment interruption.
International immunology - 1 Feb 2011
Bozzano Federica, Nasi Milena, Bertoncelli Linda, Nemes Elisa, Prati Francesca, Marras Francesco, Mussini Cristina, Moretta Lorenzo, Cossarizza Andrea, De Maria Andrea
Abstract excerpt
Long-term side effects may represent a relevant burden of antiretroviral treatment (ART) in HIV-infected patients with good CD4 immune reconstitution over extended time spans. CD4-guided treatment interruption (TI) has been evaluated to address this point and may result in a wide spectrum of time off ART in different patient cohorts. We studied whether differences in innate immune responses, in particular NK...
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