Article
A method for identifying haplotypes carrying the causative allele in positive natural selection and genome-wide association studies.
Bioinformatics (Oxford, England) - 15 Mar 2011
Ong Rick Twee-Hee, Liu Xuanyao, Poh Wan-Ting, Sim Xueling, Chia Kee-Seng, Teo Yik-Ying
Abstract excerpt
MOTIVATION: Methods for detecting positive selection relied on finding evidence of long haplotypes to identify candidate regions under selection. However, these methods generally do not identify the length and form of the selected haplotype. RESULTS: We present HapFinder, a method which can find the common longest haplotype under three different settings from a database, which is relevant in the analysis of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
