Mitosis may be an obligatory route to terminal differentiation in the Friend erythroleukemia cell.

doi:10.1016/0014-4827(90)90049-g

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Article

Mitosis may be an obligatory route to terminal differentiation in the Friend erythroleukemia cell.

Experimental cell research - 1 Nov 1990

Dinnen R, Ebisuzaki K

Abstract excerpt

In previous studies, it was shown that treatment of Friend erythroleukemia (FEL) cells with dimethylsulfoxide (DMSO) and the poly(ADP-ribose) polymerase inhibitor 3-aminobenzamide (3AB) blocked the differentiation pathway just prior to commitment. These studies show that the exposure of DMSO(+3AB...

Topics

Aphidicolin
Benzamides
Cell Survival
Demecolcine
Dimethyl Sulfoxide
Diterpenes
Erythrocytes
Hematopoiesis
Leukemia, Erythroblastic, Acute
Mitosis
Nocodazole
Phenotype
Tumor Cells, Cultured

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