Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mitosis may be an obligatory route to terminal differentiation in the Friend erythroleukemia cell.

Experimental cell research - 1 Nov 1990

Dinnen R, Ebisuzaki K

Abstract excerpt

In previous studies, it was shown that treatment of Friend erythroleukemia (FEL) cells with dimethylsulfoxide (DMSO) and the poly(ADP-ribose) polymerase inhibitor 3-aminobenzamide (3AB) blocked the differentiation pathway just prior to commitment. These studies show that the exposure of DMSO(+3AB)-induced cells to the mitotic inhibitors colcemid or nocodazole resulted in commitment to terminal differentiation....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Survival
Share to Dimethyl Sulfoxide
Share to Erythrocytes

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Hematopoiesis

Share to Leukemia, Erythroblastic, Acute

Share to Mitosis

Share to Phenotype

Share to Tumor Cells, Cultured

Source

Identifiers

PMID: 2121511
DOI: 10.1016/0014-4827(90)90049-g

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

Mitosis may be an obligatory route to terminal differentiation in the Friend erythroleukemia cell.PMID 2121511Read ↗

Temporal mapping of the differentiation pathway of the murine erythroleukemia cell.Semantic proximity Read ↗

Molecular and cellular mechanisms of leukemic hemopoietic cell differentiation: an analysis of the Friend system.Semantic proximity Read ↗

Relationship between globin mRNA accumulation and commitment to terminal cell differentiation in inducer sensitive and resistant erythroleukemia variants.Semantic proximity Read ↗

Inhibition of MEL cells' capacity to undergo erythroid differentiation by chemicals added during induction.Semantic proximity Read ↗

Mitotic cycle reactivation in terminally differentiated cells by adenovirus infection.Semantic proximity Read ↗

Alteration in proportions of histone H1 variants during the differentiation of murine erythroleukaemic cells.Semantic proximity Read ↗

The Molecular Signature of Megakaryocyte-Erythroid Progenitors Reveals a Role for the Cell Cycle in Fate SpecificationSemantic proximity Read ↗

Cdc42 regulates cell polarization and contractile actomyosin rings during terminal differentiation of human erythroblastsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.