Article
Temporal mapping of the differentiation pathway of the murine erythroleukemia cell.
Cancer research - 15 Mar 1991
Ebisuzaki K, Casley W L, Griffiths A, Wheaton L
Abstract excerpt
These studies are concerned with "mapping" the temporal order of the precommitment events in the differentiation pathway of the Friend erythroleukemia cell. We have used a single-block procedure in which a differentiation-specific inhibitor of a temperature-sensitive (ts) differentiation-defective mutation was used to block the differentiation program. Later, the block was removed, differentiation was allowed to...
Topics
- Animals
- Cell Differentiation
- Cytochalasin B
- Dexamethasone
- Dimethyl Sulfoxide
- Friend murine leukemia virus
- Leukemia, Erythroblastic, Acute
- Mice
- Mutation
- Tumor Cells, Cultured