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Article

Polymorphisms of CXCL8 and its receptor CXCR2 contribute to the development and progression of childhood IgA nephropathy.

Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research - 1 Mar 2011

Suh Jin-Soon, Hahn Won-Ho, Cho Byoung-Soo

Abstract excerpt

Many studies have suggested that CXCL8 and CXCR2 play an important role in the pathogenesis of several types of renal diseases. However, there is no prior study on the association between polymorphisms of these genes and IgA nephropathy (IgAN), especially in children. The genotyping data from 192 patients with childhood IgAN and 397 controls showed significant differences in the frequencies of the CXCL8 gene with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Glomerulonephritis, IGA

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Share to Polymorphism, Single Nucleotide

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Source

Identifiers

PMID: 21214373
DOI: 10.1089/jir.2010.0031

Genes

CXCL8
CXCR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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