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Article

Inhibition of stromal cell-derived factor-1α further impairs diabetic wound healing.

Journal of vascular surgery - 1 Mar 2011

Bermudez Dustin M, Xu Junwang, Herdrich Benjamin J, Radu Antoneta, Mitchell Marc E, Liechty Kenneth W

Abstract excerpt

OBJECTIVE: Impaired diabetic wound healing is associated with abnormal stromal cell-derived factor (SDF)-1α production, decreased angiogenesis, and chronic inflammation. Lentiviral-mediated overexpression of SDF-1α can correct the impairments in angiogenesis and healing in diabetic wounds. We hypothesized that SDF-1α is a critical component of the normal wound-healing response and that inhibition of SDF-1α would...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21211927
DOI: 10.1016/j.jvs.2010.10.056
PMCID: PMC3058337

Genes

CXCR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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