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Article

Deregulated immune cell recruitment orchestrated by FOXM1 impairs human diabetic wound healing

16 Sept 2020

Abstract excerpt

Diabetic foot ulcers (DFUs) are a life-threatening disease that often result in lower limb amputations and a shortened lifespan. However, molecular mechanisms contributing to the pathogenesis of DFUs remain poorly understood. We use next-generation sequencing to generate a human dataset of pathogenic DFUs to compare to transcriptional profiles of human skin and oral acute wounds, oral as a model of "ideal" adult...

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Share to Diabetic Foot Ulcer Assessment and Management
Share to Wound Healing and Treatments

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Identifiers

PMID: 32938916
DOI: 10.1038/s41467-020-18276-0

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