Article
The -323Ins10 polymorphism for factor VII is not associated with coronary atherosclerosis in symptomatic men. The REGRESS study group.
Thrombosis research - 1 Mar 2000
Lievers K J, Mennen L I, Rattink A P, Zwinderman A H, Jukema J W, Schouten E G, de Maat M P
Abstract excerpt
Elevated factor VII coagulant activity (FVII:C) has been associated with an increased risk of ischaemic heart disease, particularly for fatal events. Results of studies on the association between FVII:C and atherosclerosis are not consistent. FVII:C levels are influenced by several environmental factors and by genetic factors. One of the genetic factors is the -323Ins10 polymorphism in the promoter region of the...
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