Article
High rate of in-stent restenosis after coronary intervention in carriers of the mutant mannose-binding lectin allele.
BMC cardiovascular disorders - 5 Jan 2017
Bagyura Zsolt, Kiss Loretta, Berta Balázs, Szilágyi Ágnes, Hirschberg Kristóf, Széplaki Gábor, Lux Árpád, Szelid Zsolt, Soós Pál, Merkely Béla
Abstract excerpt
BACKGROUND: In-stent restenosis occurs in 10-30% of patients following bare metal stent (BMS) implantation and has various risk factors. Mannose-binding lectin (MBL) is known to have effect on the progression of atherosclerosis. Single nucleotide polymorphisms (SNP) of the MBL2 gene intron 1 (codon 52, 54, 57) are known to modulate the bioavailability of the MBL protein. Our aim was to identify the association of...
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