Article
IκB kinase regulates social defeat stress-induced synaptic and behavioral plasticity.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 5 Jan 2011
Christoffel Daniel J, Golden Sam A, Dumitriu Dani, Robison Alfred J, Janssen William G, Ahn H Francisca, Krishnan Vaishnav, Reyes Cindy M, Han Ming-Hu, Ables Jessica L, Eisch Amelia J, Dietz David M, Ferguson Deveroux, Neve Rachael L, Greengard Paul, Kim Yong, Morrison John H, Russo Scott J
Abstract excerpt
The neurobiological underpinnings of mood and anxiety disorders have been linked to the nucleus accumbens (NAc), a region important in processing the rewarding and emotional salience of stimuli. Using chronic social defeat stress, an animal model of mood and anxiety disorders, we investigated whe...
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