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Article

Analysis of interactions of Salmonella type three secretion mutants with 3-D intestinal epithelial cells.

PloS one - 29 Dec 2010

Radtke Andrea L, Wilson James W, Sarker Shameema, Nickerson Cheryl A

Abstract excerpt

The prevailing paradigm of Salmonella enteropathogenesis based on monolayers asserts that Salmonella pathogenicity island-1 Type Three Secretion System (SPI-1 T3SS) is required for bacterial invasion into intestinal epithelium. However, little is known about the role of SPI-1 in mediating gastrointestinal disease in humans. Recently, SPI-1 deficient nontyphoidal Salmonella strains were isolated from infected...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21206750
DOI: 10.1371/journal.pone.0015750
PMCID: PMC3012082

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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