Article
Spheres of Influence: Insights into Salmonella Pathogenesis from Intestinal Organoids
1 Apr 2020
Abstract excerpt
The molecular complexity of host-pathogen interactions remains poorly understood in many infectious diseases, particularly in humans due to the limited availability of reliable and specific experimental models. To bridge the gap between classical two-dimensional culture systems, which often involve transformed cell lines that may not have all the physiologic properties of primary cells, and in vivo animal...
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