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Article

Bigenotypic and biphenotypic appearance of immunoglobulin light chains in 1 of 3 non-Hodgkin's lymphoma xenografts.

Oncology - 1 Jan 1990

Kopper L, Bánkfalvi A, Földi J, Mihalik R, Magyar M, Aczél A

Abstract excerpt

Chromosomal analysis of three human non-Hodgkin's lymphoma (NHL) xenografts revealed common extra 14q+ segment and other individual clonal markers without involvement of immunoglobulin light-chain regions. Two NHL xenografts (HT 58 and HT 130) showed restricted lambda light chain expression and deleted kappa and rearranged lambda genes. However, in HT 117 both kappa and lambda chains were present on the cell...

Topics

Animals
Antibodies
Antibodies, Monoclonal
Gene Rearrangement
Genotype
Humans
Immunoglobulin Light Chains
Immunosuppression Therapy
Karyotyping
Lymphoma, Non-Hodgkin
Mice

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Phenotype

Restriction Mapping

Transplantation, Heterologous

Source

Identifiers

PMID: 2120650
DOI: 10.1159/000226855

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2120650-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Bigenotypic and biphenotypic appearance of immunoglobulin light chains in 1 of 3 non-Hodgkin's lymphoma xenografts.PMID 2120650Read ↗

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