Article
Genotypic and immunophenotypic characterization of two human light chain-only B-cell non-Hodgkin's lymphomas.
American journal of clinical pathology - 1 Oct 1990
De Re V, Carbone A, Dolcetti R, Tirelli U, Folegotto C, Boiocchi M
Abstract excerpt
Two atypical human non-Hodgkin's lymphomas (NHLs) that exhibited unusual genotypic and in situ immunophenotypic abnormalities are described. Immunophenotypically, both NHLs lacked surface Ig heavy chains. With the exception of the MB2 B-cell-associated antigen, no B- and T-cell differentiation an...
Topics
- Adult
- Antibodies, Monoclonal
- DNA, Neoplasm
- Female
- Gene Rearrangement, B-Lymphocyte, Light Chain
- Genotype
- Humans
- Immunoglobulin Light Chains
- Immunoglobulin kappa-Chains
- Immunoglobulin lambda-Chains
- Lymphoma, B-Cell
- Male
- Phenotype