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Article

Gene inactivation and its implications for annotation in the era of personal genomics.

Genes & development - 1 Jan 2011

Balasubramanian Suganthi, Habegger Lukas, Frankish Adam, MacArthur Daniel G, Harte Rachel, Tyler-Smith Chris, Harrow Jennifer, Gerstein Mark

Abstract excerpt

The first wave of personal genomes documents how no single individual genome contains the full complement of functional genes. Here, we describe the extent of variation in gene and pseudogene numbers between individuals arising from inactivation events such as premature termination or aberrant sp...

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PMID: 21205862
DOI: 10.1101/gad.1968411
PMCID: PMC3012931

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21205862-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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