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Prognostic Importance of Histone MethyltransferaseMLL5Expression in Acute Myeloid Leukemia

5 Jan 2011

Abstract excerpt

PURPOSE: To assess the prognostic importance of mixed lineage leukemia 5 (MLL5) expression in acute myeloid leukemia (AML). PATIENTS AND METHODS: MLL5 transcript levels from 509 patients with AML who were treated in multicenter trials AML SHG 0199 and AML SHG 0295 and 48 healthy volunteers were analyzed by real-time reverse-transcription polymerase chain reaction in the context of other molecular markers (NPM1,...

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PMID: 21205756
DOI: 10.1200/jco.2010.31.1118

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