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Article

Behavioural phenotyping assays for mouse models of autism.

Nature reviews. Neuroscience - 1 Jul 2010

Silverman Jill L, Yang Mu, Lord Catherine, Crawley Jacqueline N

Abstract excerpt

Autism is a heterogeneous neurodevelopmental disorder of unknown aetiology that affects 1 in 100-150 individuals. Diagnosis is based on three categories of behavioural criteria: abnormal social interactions, communication deficits and repetitive behaviours. Strong evidence for a genetic basis has prompted the development of mouse models with targeted mutations in candidate genes for autism. As the diagnostic...

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PMID: 20559336
DOI: 10.1038/nrn2851
PMCID: PMC3087436

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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