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Article

HLA-B*1502 strongly predicts carbamazepine-induced Stevens-Johnson syndrome and toxic epidermal necrolysis in Thai patients with neuropathic pain.

Pain practice : the official journal of World Institute of Pain - 1 Mar 2012

Kulkantrakorn Kongkiat, Tassaneeyakul Wichittra, Tiamkao Somsak, Jantararoungtong Thawinee, Prabmechai Napat, Vannaprasaht Suda, Chumworathayi Pansu, Chen Pei, Sritipsukho Paskorn

Abstract excerpt

BACKGROUND: Carbamazepine (CBZ) is one of the standard pharmacological treatments for neuropathic pain. However, its serious adverse drug reactions include Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN). Recently, HLA-B*1502 allele was implicated as a genetic marker of CBZ-induced SJS/TEN in some Asian epilepsy populations. METHODS: This is a case control study to describe the clinical...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21676164
DOI: 10.1111/j.1533-2500.2011.00479.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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