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Technological issues and experimental design of gene association studies.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2011

Distefano Johanna K, Taverna Darin M

Abstract excerpt

Genome-wide association studies (GWAS), in which thousands of single-nucleotide polymorphisms (SNPs) spanning the genome are genotyped in individuals who are phenotypically well characterized, -currently represent the most popular strategy for identifying gene regions associated with common -diseases and related quantitative traits. Improvements in technology and throughput capability, development of powerful...

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PMID: 21204023
DOI: 10.1007/978-1-61737-954-3_1

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