Article
Planning and executing a genome wide association study (GWAS).
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2009
Sale Michèle M, Mychaleckyj Josyf C, Chen Wei-Min
Abstract excerpt
In recent years, genome-wide association approaches have proven a powerful and successful strategy to identify genetic contributors to complex traits, including a number of endocrine disorders. Their success has meant that genome wide association studies (GWAS) are fast becoming the default study design for discovery of new genetic variants that influence a clinical trait or phenotype. This chapter focuses on a...
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