Article
Characterization of the regulatory region of the zebrafish Prep1.1 gene: analogies to the promoter of the human PREP1.
PloS one - 22 Dec 2010
Bernardi Elisa, Deflorian Gianluca, Pezzimenti Federica, Pezzinenti Federica, Diaz Victor M, Mione Marina, Blasi Francesco
Abstract excerpt
Prep1 is a developmentally essential TALE class homeodomain transcription factor. In zebrafish and mouse, Prep1 is already ubiquitously expressed at the earliest stages of development, with important tissue-specific peculiarities. The Prep1 gene in mouse is developmentally essential and has haploinsufficient tumor suppressor activity [1]. We have determined the human Prep1 transcription start site (TSS) by primer...
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