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A Genomic Survey of Positive Selection in Burkholderia pseudomallei Provides Insights into the Evolution of Accidental Virulence

1 Apr 2010

Abstract excerpt

Certain environmental microorganisms can cause severe human infections, even in the absence of an obvious requirement for transition through an animal host for replication ("accidental virulence"). To understand this process, we compared eleven isolate genomes of Burkholderia pseudomallei (Bp), a tropical soil microbe and causative agent of the human and animal disease melioidosis. We found evidence for the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 20368977
DOI: 10.1371/journal.ppat.1000845

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