Article
Differences in the ability to suppress interferon β production between allele A and allele B NS1 proteins from H10 influenza A viruses.
Virology journal - 31 Dec 2010
Zohari Siamak, Munir Muhammad, Metreveli Giorgi, Belák Sándor, Berg Mikael
Abstract excerpt
BACKGROUND: In our previous study concerning the genetic relationship among H10 avian influenza viruses with different pathogenicity in mink (Mustela vison), we found that these differences were related to amino acid variations in the NS1 protein. In this study, we extend our previous work to further investigate the effect of the NS1 from different gene pools on type I IFN promoter activity, the production of...
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