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Article

Differential RNA silencing suppression activity of NS1 proteins from different influenza A virus strains

10 Jul 2009

Abstract excerpt

The NS1 gene of influenza A virus encodes a multi-functional protein that plays an important role in counteracting cellular antiviral mechanisms such as the interferon (IFN), protein kinase R and retinoic acid-inducible gene product I pathways. In addition, NS1 has recently been shown to have RNA interference (RNAi) or RNA silencing suppression (RSS) activity. This study analysed the IFN antagonistic activity of...

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PMID: 19369407
DOI: 10.1099/vir.0.008284-0

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