Article
Determinants of chemotactic signal amplification in Escherichia coli.
Journal of molecular biology - 16 Mar 2001
Kim C, Jackson M, Lux R, Khan S
Abstract excerpt
A well-characterized protein phosphorelay mediates Escherichia coli chemotaxis towards the amino acid attractant aspartate. The protein CheY shuttles between flagellar motors and methyl-accepting chemoreceptor (MCP) complexes containing the linker CheW and the kinase CheA. CheA-CheY phosphotransfer generates phospho-CheY, CheY-P. Aspartate triggers smooth swim responses by inactivation of the CheA bound to the...
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