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Article

Inter-ethnic variability of three functional polymorphisms affecting the IMPDH2 gene.

Molecular biology reports - 1 Nov 2011

Garat Anne, Cardenas Christian Lacks Lino, Lionet Arnaud, Devos Aurore, Glowacki François, Kenani Abderraouf, Migot-Nabias Florence, Allorge Delphine, Lo-Guidice Jean-Marc, Broly Franck, Cauffiez Christelle

Abstract excerpt

Human type II inosine monophosphate dehydrogenase (IMPDH2) is a key enzyme in the purine nucleotide biosynthetic pathway and constitutes a pivotal biological target for immunosuppressant and antiviral drugs. Several Single Nucleotide Polymorphisms (SNP) affecting the IMPDH2 gene sequence have been reported with potential functional relevance and could impact drugs response. We aimed to determine the frequency of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21181270
DOI: 10.1007/s11033-010-0668-z

Genes

IMPDH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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