Article
Interpopulation variation frequency of human inosine 5'-monophosphate dehydrogenase type II (IMPDH2) genetic polymorphisms.
Genetic testing - 1 Dec 2008
Mohamed M F, Frye Reginald F, Langaee Taimour Y
Abstract excerpt
Inosine monophosphate dehydrogenase type II (IMPDH2) is the target for immunosuppression by mycophenolic acid and has been linked to resistance of tumor cells to chemotherapy. Determining the frequency of IMPDH2 genetic polymorphisms can inform the design of clinical studies investigating the impact of IMPDH2 genetic variability on both cancer therapy and immunosuppression. Frequencies of three IMPDH2...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
