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Article

Pharmacogenomics of statin therapy: any new insights in efficacy or safety?

Current opinion in lipidology - 1 Dec 2014

Hopewell Jemma C, Reith Christina, Armitage Jane

Abstract excerpt

PURPOSE OF REVIEW: To examine the current evidence concerning the effects of genetic variation on statin-related low-density lipoprotein cholesterol reductions, clinical efficacy, and adverse events and the relevance for patient care. RECENT FINDINGS: Recent years have seen the emergence of large-scale genetic experiments, including genome-wide association studies and candidate gene studies, exploring the impact...

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PMID: 25313593
DOI: 10.1097/MOL.0000000000000125

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